What is Afanix?
Afatinib is a kinase inhibitor used in the treatment of non-small cell lung cancer. As first-line therapy (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) 19 deletions or substitutions of exon 21 (L858R).
Patients with non-small cell lung cancer often undergo radiotherapy and chemotherapy. Afanix is a late-stage cancer drug that targets a mutated gene.
Afanix is manufactured by Beacon Bangladesh Pharmaceutical Company.
Active ingredient: Afatinib 40mg
Specification: Box of 3 blisters / 10 tablets.
Origin: Beacon Bangladesh.
What does Afanix do?
Many cancer cells have structures called epidermal growth factor receptor (EGFR) and growth factor receptor 2 (HER2) on their surface.
These receptors allow a protein called epidermal growth factor (EGF) to attach to cells. When epidermal growth factor binds to the receptor, it activates an enzyme in the cell called tyrosine kinase.
This enzyme activates chemical processes inside cancer cells that cause the cells to grow and multiply.
Afanix Active ingredient Afatinib works by binding to the HER2 and EGFR receptors found on cancer cells. This prevents EGF from activating them and as a result stops cancer cells from growing and multiplying.
Afatinib is indicated for the treatment of non-small cell lung cancer (NSCLC). Afanix is only effective against NSCLCs with EGFR mutations on the surface of cancer cells.
You need to have an EGFR mutation test before you start treatment with Afanix.
Dosage and how to take Afanix?
The recommended dose is one Afanix 40 mg tablet per day.
Your doctor may adjust (increase or decrease) your dose in 10 steps depending on how well you tolerate Afanix.
If you have severe diarrhea or other intolerable side effects. Your doctor may stop treatment with Afanix and then restart treatment at a lower dose.
How to take Afanix 40mg?
Swallow the tablet whole with a full glass of water. Do not chew or crush the tablet.
For patients who have difficulty swallowing, the tablet can be dissolved in (non-carbonated) drinking water. No other liquid should be used. Follow the instructions carefully:
- Drop the tablet in half a glass of drinking water (non-carbonated) (Do not break or crush the tablet)
- Stir the water occasionally for up to 15 minutes until the tablet breaks into very small particles
- Drink immediately
- Rinse the empty glass with half a glass of drinking water and drink.
When to take Afanix?
Take the medicine at about the same time each day.
Use at the same time every day for best results. It will also help you remember when to take it.
Take the medicine on an empty stomach. Do not eat for at least 3 hours before taking the medicine and at least 1 hour after taking the medicine.
Food may interfere with the absorption of this medicine.
Forgot to take Afanix
If you forgot to take it
If it is less than 8 hours before your next dose, skip the dose you missed and take your next dose when you are meant to.
If not, take it as soon as you remember, and then go back to taking it as usual.
Do not take a double dose to make up for the dose you missed. This can increase your chances of getting an unwanted side effect.
See more:
https://thuoclp.com/thuoc-ung-thu/ung-thu-phoi/thuoc-afanix-40mg/
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