Avastin 400mg / 16ml Bevacizumab for cancer treatment | ThuocLP Vietnamese Health
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Avastin 400mg / 16ml Bevacizumab intravenous solution for cancer treatment
Brand Name: Avastin 400mg / 16ml
Active ingredient: Bevacizumab
Manufacturer: ROCHE
Content: 400mg / 16ml
Form: Injections
Packing: Box of 400mg / 16md infusion
Avastin Drug Price: Comment below for price OR Click on the link: https://thuoclp.com/chatFB type “Avastin”
Avastin 400mg16ml Bevacizumab for cancer treatment (3)
What is Avastin? What disease is Bevacizumab indicated for?
The drug Avastin (Bevacizumab) is used with chemotherapy to treat cancer of the colon (large intestine) or rectum that has spread to other parts of the body.
Bevacizumab is also used with chemotherapy to treat certain types of lung cancer.
The drug Avastin (Bevacizumab) is also used to treat spongioblastoma (a type of brain tumor) that has already been treated with other drugs.
Bevacizumab is also used in combination with other drugs to treat kidney cell cancer (RCC, a cancer that starts in the kidneys) that has spread to other parts of the body.
The drug Avastin (Bevacizumab) is a drug called an anticholinergic agent. It works by stopping the formation of blood vessels that carry oxygen and nutrients to tumors. This can slow the growth and spread of tumors.
Contraindicated
Hypersensitivity to the drug ingredients or products from Chinese guinea pigs, recombinant human antibodies or other anthropomorphic antibodies. There is metastasis to the untreated TKTW system.
Careful
There is a risk of bleeding;
recently had pulmonary hemorrhage, coughing up blood;
history of arterial thromboembolism,> 65t;
the risk of venous thromboembolism of grade 3 or less;
Severe cardiovascular disease / pre-existing congestive heart failure.
Pregnancy, lactation.
Important Information Medication Avastin 400mg
Avastin can make it easier for you to bleed. Contact your doctor or seek emergency medical attention if you have any bleeding that will not stop. You may also have bleeding inside the body , such as in your stomach or intestines, or in your brain.
Call your doctor at once if you have: signs of bleeding in your gastrointestinal tract - feeling very weak or dizzy stomach pain, severe stomach pain, black or bloody stools, or if you cough up blood or vomit coffee varieties; or signs of bleeding in the brain - sudden sudden or weakening of weakness (especially on one side of the body), sudden severe headache, or problems with vision or balance.
Avastin can also cause problems with wound healing, which can lead to bleeding or infection. Do not use this medicine within 28 days before or after a planned surgery.
Avastin can cause a rare but serious neurological disorder that affects the brain. Symptoms include headache, confusion, problems with vision, feeling very weak or tired, fainting, and seizures (blackout or convulsions). These rare symptoms may occur within the first few hours of the Avastin dose, or they may not appear for a year after treatment has started. Call your doctor at once if you have any of these side effects.
Some people who get Avastin have had a reaction to the infusion (when the drug is injected into the vein). Tell your caregiver right away if you experience dizziness, nausea, headaches, itching, or a fast heartbeat, chills, wheezing, or chest pain during the injection.
Avastin can cause a woman's ovaries to stop working properly. Ovarian failure symptoms include 3 or more missed menstrual cycles. This may affect your fertility (your ability to have children). Talk to your doctor about your specific risks.
Note before taking Avastin 400mg
You should not use Avastin if you are allergic to bevacizumab, or:
if you have healed a skin wound or surgical incision;
if you have had surgery within the past 4 weeks (28 days);
if you have recently coughed up blood; or
if you plan on having surgery within the next 4 weeks (28 days).
To make sure Avastin is safe for you, tell your doctor if you:
heart disease, high blood pressure;
a history of heart attack, stroke, or blood clot;
bleeding or blood clotting disorder; or
a history of stomach or intestinal bleeding, or perforation (pit or hole) in the esophagus, stomach, or intestines.
It is not known whether Avastin will harm an unborn baby. In animal studies, Bevacizumab caused birth defects. However, it is not known whether these effects occur in humans. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your treatment ends.
Avastin can cause a woman's ovaries to stop working properly. Ovarian failure symptoms include 3 or more missed menstrual cycles. This may affect your fertility (your ability to have children). Talk to your doctor about your specific risks.
It is not known whether bevacizumab passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are being treated with Avastin.
How is Avastin given?
Avastin is injected into a vein through an IV. A medical provider will give you this injection.
Some people who get Avastin have had a reaction to the infusion (when the drug is injected into the vein). Tell your caregiver if you experience dizziness, nausea, lightheadedness, sweating, or headache, shortness of breath, or chest pain during the injection.
Avastin is usually given every 2 or 3 weeks.
Your blood pressure will need to be checked often. The concentration of protein in your urine may also need to be checked.
Avastin can cause problems with wound healing, which can lead to bleeding or infection. If you need any type of surgery, you will need to stop using Avastin at least 28 days before the deadline. Do not start using Avastin for at least 28 days after surgery, or until your surgical wound has healed.
Note when infusing Avastin 400mg
Not used when administered intravenously or intravenously. For intravenous (IV) use only.
Do not start Avastin until at least 28 days after major surgery. Administer Avastin after the surgical incision has completely healed.
First infusion: Use for 90 minutes.
Infusion later: Second infusion over 60 minutes if the first solution is tolerated; administer all subsequent infusions over 30 minutes if infusion solution over 60 minutes is tolerated.
Avastin 400mg16ml Bevacizumab for cancer treatment (1)
Recommended dosage Avastin 40mg
Patients should continue treatment until disease progression or intoxication is not accepted.
Colorectal Cancer (MCRC)
The recommended dose is 5 mg / kg or 10 mg / kg every 2 weeks when used in conjunction with intravenous chemotherapy 5-FU.
Use 5 mg / kg when combined with bolus-IFL.
Use 10 mg / kg when used in combination with FOLFOX4.
Treatment of 5 mg / kg every 2 weeks or 7.5 mg / kg every 3 weeks when used in combination with fluoromaticrimidine-irinotecan chemotherapy or fluoropyrimidine-oxaliplatin in patients progressed to first-line Avastin-containing regimen.
Non-Small Cell Lung Cancer (NSCLC)
The recommended dose is 15 mg / kg every 3 weeks in combination with carboplatin and paclitaxel.
Glioblastoma
The recommended dose is 10 mg / kg every 2 weeks.
Metastatic renal cell cancer (mRCC)
The recommended dose is 10 mg / kg every 2 weeks in combination with interferon alfa.
Cervical cancer
The recommended dose of Avastin is 15 mg / kg every 3 weeks when given intravenously in combination with one of the following treatment regimens: paclitaxel and cisplatin, or paclitaxel and topotecan.
Psoriasis presents as recurrent white blood cells, fallopian tubes, or primary peritoneal cancer
The recommended dose is 10mg / kg every 2 weeks in combination with one of the following chemical treatment regimens: paclitaxel, pegylated liposomal doxorubicin, or topotecan (weekly); or 15 mg / kg every 3 weeks in combination with topotecan (every 3 weeks).
Gourd recurrence Platinum, Fallopian Sugar, or Primary Peritoneal Cancer
The recommended dose is 15 mg / kg every 3 weeks when used in combination with carboplatin and paclitaxel for 6 cycles and up to 8 cycles, followed by continued use of Avastin 15 mg / kg every 3 weeks as a donor agent. to progression. Additionally, 15 mg / kg every 3 weeks when used in combination with carboplatin and gemcitabine for 6 cycles and up to 10 cycles, followed by continued administration of Avastin 15 mg / kg every 3 weeks as an agent up to disease progression.
Prepare for the infusion of Avastin
Use the appropriate aseptic technique. Parenteral products should be visually inspected for particulate matter and discoloration prior to use, whenever the solution and solvent allows. Withdraw the required amount of Avastin and dilute to a total volume of 100 mL 0.9% Sodium Chloride Injection, USP. Discard any unused portion remaining in the jar, as the product does not contain preservatives.
What if I miss a dose
Call your doctor for instructions if you miss an appointment for an Avastin injection.
What if I overdose
Go to the nearest medical facility or call 115.
What should I avoid while taking Avastin
Avoid activities that increase your risk of bleeding or injury. Use care to avoid bleeding while shaving or brushing teeth.
Side effects of Avastin
Ask for emergency medical help if you have signs of an allergic reaction to Avastin : hives; shortness of breath; swelling of your face, lips, tongue, or throat.
Avastin can make it easier for you to bleed. Call your doctor or seek urgent medical attention if you:
easy bruising, unusual bleeding (nose, mouth, vagina, rectum) or any bleeding that won't stop;
signs of bleeding in your digestive tract - severe stomach pain, bloody or delayed stools, coughing up blood or vomiting that looks like coffee grounds; or
signs of bleeding in the brain - sudden suddenness or weakness (especially on one side of the body), sudden headache, problems with vision or balance.
Avastin can cause a rare but serious neurological disorder that affects the brain. Symptoms may occur within hours of your first dose, or they may not appear within a year after treatment has started. Call your doctor at once if you have weakness or fatigue, headache, confusion, problems with vision, fainting or seizures (power loss or convulsions).
Some people receiving Avastin have developed a fistula (abnormal pathway) in the throat, lungs, gallbladder, kidneys, bladder, or vagina. Call your doctor if you have: chest pain and difficulty breathing, stomach pain or swelling, urine flow, or if you feel suffocated while eating or drinking.
Also call your doctor if you are
fever, chills, vomiting and constipation;
swollen gums, burning pain, pain when swallowing, skin ulcers, cold or flu symptoms, cough;
pain, swelling, heat, or redness in one or both legs;
chest pain or severe feeling, pain spreading to your jaw or shoulder, nausea, sweating, feeling sick;
missed menstrual periods;
signs of any skin infection - sudden red, red, hot, swollen, or oozing, or any skin wound or surgical incision will not heal; or
dangerously high blood pressure - severe headache, blurred vision, neck pain, earache, nosebleeds, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeat.
Older adults may be more likely to have side effects from this medication.
Other drugs may interact with bevacizumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Avastin 400mg16ml Bevacizumab for cancer treatment (2)
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How much is the price of Avastin 400mg / 16ml Bevacizumab?
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Note: Information about the drug Avastin 400mg / 16ml Bevacizumab is intended to share knowledge for reference purposes, patients are not allowed to arbitrarily use drugs, all information on drug use must be prescribed by a specialist doctor. subject.
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