Bonviva 150mg ibandronic supplement to treat low blood pressure after menstruation (3)
Bonviva 150mg ibandronic acid
The drug Bonviva is an active substance containing ibandronic acid. It is available as tablets (150mg) and as a solution for injection in a prefilled syringe (3 mg).
Drug Bonviva 150mg is used to treat what disease? How long to use the drug bonviva
Bonviva is used to treat osteoporosis (a disease that makes bones more fragile) in women who have gone through menopause and are at risk for developing fractures (breaking down).
Its effects in reducing the risk of spinal fractures have been demonstrated in studies, but its effect on the risk of fracture of the femoral neck (the top of the femur) has not been established.
The drug is for sale and use only as directed.
What should you consider before taking bonviva 150mg ibandronic?
Do not take Bonviva pills
If you are allergic (hypersensitive) to ibandronic acid, or to any of the other ingredients of Bonviva.
If you have certain problems with your esophagus (the tube that connects your mouth to your stomach) such as narrow or difficulty swallowing.
If you are unable to stand or sit upright for at least one hour (60 minutes) at a time.
If you have, or in the past, low blood calcium. Please consult your physician.
Children and teenagers
Take special care with Bonviva
Some people need to be especially careful while they are taking Bonviva. Check with your doctor:
If you have any mineral metabolism disorders (such as vitamin D deficiency).
If your kidneys are not working properly.
If you have any problems swallowing or digesting.
If you are having dental treatment or are going to undergo dental surgery, tell your dentist that you are being treated with Bonviva.
Irritation, inflammation, or ulceration of the esophagus (the tube connecting the mouth to your stomach) often has severe chest pain, severe pain after swallowing food and / or drinking, severe nausea or vomiting, especially is if you do not drink a full glass of water and / or if you lie down within one hour of taking Bonviva.
If you develop these symptoms, stop taking Bonviva and tell your doctor right away.
Take another medicine
Please let your doctor or pharmacist know if you are taking, or have recently taken any other medicines, including drugs obtained without a prescription. Especially:
Supplements contain calcium, magnesium, iron, or aluminum, as they may interfere with Bonviva's effects. Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) (including ibuprofen, diclofenac sodium, and naproxen) can irritate the stomach and intestines. Bisphosphonates (like Bonviva) can also do the same. So, be especially careful if you take pain relievers or anti-inflammatory drugs while you are taking Bonviva.
After swallowing your monthly Bonviva tablet, wait for 1 hour before taking any other medicine, including indigestion pills, calcium or vitamin supplements.
Drink Bonviva with food and drink
Do not take Bonviva with food. Bonviva is less effective if taken with food. You can drink filtered water but there are no other drinks
Pregnancy and lactation
Do not take Bonviva if you are pregnant or breast-feeding. If you are breast-feeding, you may need to stop to take Bonviva. Ask your doctor or pharmacist for advice before taking any medicine.
Driving and using machines
You can drive and use machines because it is very unlikely that Bonviva will affect your ability to drive and use the machine.
Bonviva 150mg ibandronic pills for low-pressure treatment after menstruation (2)
How to use ibandronic acid bonviva 150mg for effective
The drug Bonviva is in the form of tablets for oral administration or as an infusion / intravenous solution.
Tablets: dosage is 1 tablet / month, taken at the same day every month. Should drink 1 hour before eating with plenty of water. (In areas with hard water, where tap water contains a lot of dissolved calcium, bottled water with a low mineral content may be used.) The patient should not lie down for one hour after taking the medication.
Intravenous form: The dose by injection is 3 mg 1 time every 3 months. Patients taking Bonviva should also take vitamin D and calcium supplements if they are not getting enough from their diet.
How does bonviva 150mg ibandronic work?
Osteoporosis occurs when not enough new bone develops to replace the bone that is naturally broken. Gradually, the bones become thin and fragile, and more likely to break. Osteoporosis is more common in postmenopausal women, when levels of the female hormone estrogen drop, because estrogen helps keep bones healthy.
The active substance in Bonviva, ibandronic acid, is a bisphosphonate. It stops the action of osteoclasts, the cells involved in breaking down bone tissue. Blocking the action of cells leads to less bone loss.
Studies on the drug bonviva 150mg ibandronic for osteoporosis treatment
Bonviva has been studied in 3 main studies involving women with osteoporosis.
The first study compared Bonviva tablet 2.5 mg once-a-day with placebo (a dummy treatment) in nearly 3,000 women and looked at how many new spinal fractures were seen in patients within three years. .
Two other studies compared the 150 mg monthly Tablets (1,609 patients) and injections (1,395 patients) with 2.5 mg of the drug once a day. Studies have looked at changes in bone density in the spine and hip for more than two years.
2.5 mg of the drug once a day used in discontinued studies.
What is the benefit of Bonviva during the studies?
In the first study, daily treatment with Bonviva 2.5 mg tablet reduced the risk of new spinal fractures by 62% compared with placebo.
Two other studies showed that oral 150 mg monthly tablet and injection were more effective than 2.5 mg once a day on increasing bone density in the spine and hip.
Over two years, bone density in the spine increased by 7% with the monthly pill and 6% with the injection, compared with 5% with the daily pill. In the hip, bone density increased by 4% with the monthly tablets and 3% with the injection, compared with 2% with the daily tablets.
Undesirable effects during the use of the drug bonviva 150mg ibandronic acid
The most common side effects with Bonviva (seen in 1 to 10 patients in 100) are joint pain (joint pain) and flu (flu) -like symptoms.
The most serious side effects with Bonviva are anaphylaxis (severe allergic reaction), atypical fractures of the femur (a type of fracture muscle abnormality of the bones of the upper leg), bone necrosis. Jaw (damage to the bones of the jaw, which can lead to pain, sores in the mouth or loose teeth), digestive (stomach and intestines) irritation and inflammation of the eyes. For the complete list of all side effects reported with Bonviva, see the package leaflet.
Bonviva should not be used in patients with hypocalcemia (low blood calcium levels). Candles should not be used in patients with abnormalities of the esophagus or who cannot stand or sit upright for at least an hour. For the full list of restrictions with Bonviva, see the package leaflet.
Why was Bonviva approved?
The CHMP decided that Bonviva's benefits outweigh the risks and recommended that it be authorized for marketing.
Are measures being taken to ensure the safe and effective use of Bonviva?
A risk management plan has been developed to ensure that Bonviva is used as safely as possible.
Based on this plan, safety information has been included in the product specification summary and package leaflet for Bonviva, including appropriate precautions to be followed by care professionals. health care and patient.
In addition, marketing firm Bonviva will provide a card to inform patients receiving Bonviva infusion about the risk of osteonecrosis of the jaw and direct them to contact their doctor if they have symptoms.
Notes during the use of bonviva 150mg ibandronic acid
Correct bone or mineral metabolic disorders first, maintain adequate levels of calcium and vitamin D.
CKD; Monitor renal function, serum calcium, phosphate and magnesium. Heart disease; avoid dehydration. The risk of osteoporosis of the jaw is rare; provide warning cards and advise patients to maintain good oral hygiene, participate in routine dental exams, avoid dental invasions, and report oral symptoms.
Make sure dental problems are resolved before starting treatment. Rare osteoporosis risk of the outer ear canal; advise patients to report ear pain, discharge from hospital, or infection.
The risk of atypical femoral fracture is rare; Advise patient to report thigh, hip, or groin pain.
In addition, upper GI disorder; warn patients about the risk of esophageal problems, especially if not taking the correct dose and report any symptoms such as difficulty swallowing, back pain, heartburn worsens. Stop immediately if it occurs.
How long will i use bonviva 150mg ibandronic acid?
It is important to continue taking Bonviva every month, as long as your doctor prescribes it for you. Bonviva can only treat osteoporosis as long as you keep taking it.
If you take too much Bonviva
If you take many pills by mistake, drink a full glass of milk and talk to your doctor right away.
Don't make yourself vomiting, and don't lie down? This can cause Bonviva to stimulate your esophagus.
If you miss a dose
If you forget to take your tablet in the morning of the day you choose, don't take it at the end of the day. Instead, consult your calendar and find out when your next planned dose is:
What if your next expected dose is only 1 to 7 days?
You should wait until the next expected dose is due and take it as usual; After that, continue using one tablet once a month on the scheduled dates that you have marked on your calendar.
If your next scheduled dose is more than 7 days?
You should take one pill the next morning after the date you remember, then continue taking one pill once a month on the scheduled dates you have marked on your calendar.
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