Coversyl 5mg Perindopril arginine for the treatment of cardiovascular blood pressure | THUOCLP

 

What is Coversyl 5mg?

Coversyl contains the active ingredient perindopril 5mg; indicated for treatment of hypertension, congestive heart failure; is an enzyme inhibitor that converts angiotensine I to angiotensine II, a vasoconstrictor that also stimulates aldostérone secretion in the adrenal cortex.

Information Blood pressure drug Coversyl 5mg 

  • Brand Name: Coversyl 5mg.
  • Registration Number: VN-17087-13.
  • Active ingredient: each film-coated tablet contains 3,395mg perindopril (equivalent to 5mg perindopril arginin).
  • Excipients: lactose monohydrate , magnesium stearate, maltodextrin, colloidal silica, sodium glycolate (type A), glycerol, hypromellose, copper chlorophyllin, macrogol 6000, titanium dioxide.
  • Content: 5mg.
  • Packing: 1 box of 30 tablets.
  • Dosage Form: Film-coated tablets.
  • Coversyl Drug Prices: COMMENTS below for pricing.
Coversyl 5mg Perindopril arginine for heart disease therapy (3)
Coversyl pills 5mg for heart disease treatment (3)

Indications for treatment

  • Medications are used to lower high blood pressure caused by genetic or environmental factors.
  • It is used to treat heart failure because it cannot pump blood well enough to supply all the blood needed throughout the body.
  • Coversyl 5mg is used in the treatment of stable coronary artery disease to reduce the risk of cardiovascular death and heart attack.
  • It helps to control blood pressure, heart failure, or coronary artery disease, but does not cure it.

Contraindicated for use

  • Do not use Coversyl in patients who are allergic to any of the ingredients in this medication.
  • Coversyl should not be used by pregnant or lactating women.
  • Use of the drug in children and adolescents under 18 years is not recommended.

Dosage of the drug Coversyl 5mg

High Blood Pressure

  • The recommended dosage is: 5 mg once a day. After a month, this can be increased to 10 mg once a day if necessary. 10 mg per day is the maximum recommended dose for high blood pressure.
  • Patients over 65 years of age: The usual starting dose is 2.5 mg once daily. After a month it can be increased to 5 mg once a day and then if necessary to 10 mg once a day.

Heart failure

  • Starting dose is: 2.5 mg once a day.
  • After two weeks it can be increased: 5 mg once a day, which is the maximum recommended dose for heart failure.

Stable coronary artery disease

  • The starting dose is: 5 mg once a day. After two weeks it can be increased to 10 mg once a day, which is the maximum recommended dose in this indication.
  • Patients over 65 years of age: the usual starting dose is 2.5 mg once daily. After one week it can be increased to 5 mg once a day and after another week to 10 mg per day.

How to use the drug

  • Use medication exactly as directed by your doctor.
  • Coversyl pills are usually used once a day.
  • Take the tablet whole with water, preferably in the morning before meals.

What to do in case of an overdose of Coversyl 5mg?

  • Call 911 or go to the nearest local Medical Station right away.
  • Of course, you need to keep a record and bring a list of all the medications you have taken, including prescription and over-the-counter medications.

What to do if I miss a dose?

  • If you forget to take a dose, take it as soon as possible.
  • But if it is almost like the next dose, skip the missed dose and take your next dose at the time as planned.
  • Do not take double the prescribed dose.

Drug interactions and other interactions

Aliskiren : Do not take Coversyl aliskiren combined with an increased risk due to serious side effects. Some other drugs that may interact with Perindopril cause serious side effects, including:

  1. Gengraf, Neoral or Sandimmune (cyclosporine);
  2. Thiazide diuretics (water pills);
  3. Heparin;
  4. Lithuania (lithium);
  5. Nonsteroidal anti-inflammatory drugs (NSAIDS) such as: Advil or Motrin (ibuprofen) and Indocin (indomethacin)
  6. Insulin and other diabetes medicines;
  7. Gold injection for arthritis;
  8. Over-the-counter drugs that contain stimulants (this can include weight loss pills and cold medicine).

Food interactions

A diet high in potassium should be avoided during treatment with this drug due to the increased risk of serious side effects. Food, alcohol, and tobacco can interact with certain drugs. Consult your doctor about taking medication with food, alcohol and tobacco.

Coversyl 5mg Perindopril arginine for cardiopulmonary therapy (1)
Coversyl 5mg Perindopril arginine for cardiopulmonary therapy (1)

Side effects of Coversyl antihypertensive drugs

Common side effects of Coversyl blood pressure medications:

  • Headache; Mild dizziness;
  • Mild diarrhea;
  • Pain in the arm or leg;
  • Backache;
  • Dry cough;
  • Mild stomach pain;
  • Snivel.

More serious side effects you may experience when using Medindex Tablet:

  • Severe dizziness, fainting, or dizziness;
  • Swelling of hands, ankles, feet, or lower legs;
  • Signs of infection, which may include fever, sore throat, or chills;
  • Stomachache;
  • Jaundice of the skin or eyes;
  • Dark color urine;
  • Pale stools;
  • Loss of appetite;
  • Muscle pain, weakness, or cramps;
  • Red, swollen, blistering, or peeling skin;
  • Shortness of breath;
  • Stutter;
  • Chest pain, jaw pain, or arm pain;
  • Reduced or difficult urination;
  • Fast, slow, or irregular heartbeat;
  • Severe headache;
  • Signs of anaphylaxis, a severe allergic reaction may include: itching, hives, difficulty swallowing or breathing, hoarseness, tightness in the chest, or swelling of the mouth, face, lips, tongue, or throat.

Tell your doctor right away if you experience any of the symptoms listed in the Coversyl Warnings section of any of the serious side effects above.

Kidneys while using the drug Coversyl

You should not use this medicine if you are allergic to the active ingredient perindopril or if:

  • You have hereditary angioedema;
  • You are using the drug sacubitril;
  • You are allergic to any other ACE inhibitor, such as: benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, quinapril, ramipril, or trandolapril.

Do not take Coversyl 5mg within 36 hours before or after taking a medicine containing sacubitril.

If you have diabetes, do not use it with any medicine that contains aliskiren (blood pressure medicine).

You may also need to avoid taking perindopril with aliskiren if you have kidney disease.

Tell your doctor if you have ever:

  • kidney disease (or if you are on dialysis);
  • liver failure ;
  • heart disease or congestive heart failure;
  • Diabetes; or
  • connective tissue diseases such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma or rheumatoid arthritis.

Do not use if you are pregnant and breast-feeding. Consult a doctor.

Pregnant women - women who are breast-feeding

Do not use Coversyl if you are pregnant and tell your doctor right away. The active ingredient perindopril contained in the medicine can cause injury or death to the unborn baby if you take it during the second or third trimester.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risks.

How much is Coversyl 5mg?

Currently on the market, the price of Coversyl 5mg, box of 30 tablets, is priced at VND 6,800 / tablet - VND 201,000 / box.

Drug storage

  • You should store the drug at room temperature, dry, avoid direct sunlight exposure.
  • You should not store the medicine in the refrigerator.
  • Keep medicine out of reach of children.
  • You do not throw medications in the toilet or plumbing pipes.

Due date

Shelf life 36 months from date of manufacture.

Producer

SANOFI WINTHROP INDUSTRIE.
6, boulevard de Europe.
21800 Scanigny, Phap.

Coversyl 5mg Perindopril arginine for cardiopulmonary therapy (2)
Coversyl pills 5mg for heart disease treatment (2)

Note: The information in the above article on perindopril is related to its effects and its use for the purpose of sharing knowledge and introducing information about the drug to health professionals and patients. reference. Depending on the situation and the location, there will be a separate prescription and treatment. Patients are not allowed to arbitrarily use drugs, all information on drug use must be prescribed by professional doctors.

Disclaimer: ThuocLP's goal is to provide readers with relevant and up to date information. However, because drugs interact differently from person to person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always talk with your doctor or health care provider about possible interactions with all prescription medications, vitamins, herbs, and over-the-counter supplements and medications you are taking.

The author, Dr. Tran Ngoc Anh

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