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Crizotinib 250mg Crizotinib for cancer treatment (2)
What is Crizonix? What is Crizotinib?
Crizonix drug is the first Generic drug of the active ingredient Crizotinib. Crizonix is indicated as the treatment of non-small cell lung cancer (ALK) and ROS-1 positive NSCLC. Crizotinib is an inhibitor of ALK and ROS-1 (c-ros oncogen 1 receptor tyrosine kinase).
Special features of Crizonix-Crizotinib
Produced in a specialized oncology facility
The quality of the drug Crizonix is equivalent to the international standard GMP standard
Affordable for all patients
Crizonix is a cancer medicine that helps to hinder the growth and spread of cancer cells in the body.
The drug is used to treat non-small cell lung cancer. which has spread to other parts of the body.
How does Crizonix work in ALK NSCLC?
Advances in genetic research have shown that Non-Small Cell Lung Cancer (NSCLC) is not a disease, but a variety of cancers with specific genetic differences. Due to these small but important differences it is possible to develop lung cancer drugs that target specific genes, such as lymphoma (ANAPlastic lymphoma kinase - ALK).
Everyone has the ALK gene in their cells. When part of it breaks down and gathers in the wrong way, it becomes an abnormal ALK gene. This can cause cells to multiply out of control and cause a type of lung cancer to develop. This type of lung cancer is called ALK-positive (ALK) NSCLC.
Crizotinib treats ALK NSCLC that has spread to other parts of the body. By blocking the activity of the abnormal ALK gene, Crizotinib 250mg Crizotinib can shrink or slow the growth of tumors.
How does Crizonix work in ROS-1 NSCLC?
The genus ROS-1 produces a protein called ROS, which is found in the membranes of human cells. The ROS protein plays an important role in cell growth and specialization. Abnormalities in the ROS-1 gene can lead to a type of lung cancer called non-small cell lung cancer (NSCLC).
About 1% to 2% of patients with NSCLC have an abnormality in which the ROS-1 gene is combined with parts of another gene. The so-called "ROS-1 displacement" is more common in lung cancer patients who are non-smokers and are relatively young (average age 50 years).
In normal cells, the ROS-1 gene produces a protein that regulates cell growth and division. When the ROS-1 gene binds to another gene, the modified DNA sequence produces an abnormal protein that can cause uncontrolled cell growth, leading to cancer growth. The ROS protein and a protein called ALK have the same structure and function.
Crizotinib 250mg Crizotinib for cancer treatment (3)
How to take Crizotinib?
Crizonix (Crizotinib) is a pill you take twice a day, with or without food. If your doctor prescribes CRIZITONIB, make sure you:
Take medication exactly as prescribed by your doctor.
swallow the Crizonix whole.
do not change your dosage or stop taking Crizotinib unless your doctor tells you to.
Do not take more than 1 dose of Crizonix at a time.
Do not drink grapefruit juice or eat grapefruit as long as you are on medication. It can cause the amount of Crizotinib in your blood to increase to harmful levels.
Call your doctor right away if you drink too much Crizonix.
Crizotinib should be taken twice a day, without interruption. In other words, there is no "cycle" or scheduled time when you should stop taking Crizotinib and then start taking it again. Your doctor will regularly check your blood and heart during treatment.
What if you miss a dose?
If you miss a dose of Crizotinib 250mg CRIZITONIB, take it as soon as you remember if your next dose is less than 6 hours away.
In that case, simply take the next pill at your usual time. However, be sure to tell your doctor or nurse about the missed dose during your next visit.
If you are vomiting after taking a single dose of Crizotinib 250mg CRIZITONIB, don't take an extra dose, just take the next dose at your usual time.
What are the side effects of Crizotinib Crizotinib 250mg?
The most common side effects of Crizonix include:
Vision problems
These problems usually occur within 1 week of starting the medication. Crizotinib may change your eyesight or make you feel tired or dizzy. If you have these symptoms, avoid driving a vehicle, using machinery or doing anything that requires you to warn.
Other side effects of the Crizonix 250mg CRIZITONIB include:
Diarrhea;
Nausea;
Vomiting;
Constipation;
Swelling of your hands and feet;
Increased liver enzymes may indicate liver damage;
Acute respiratory failure;
Loss of appetite;
Taste changes.
The drug also causes serious side effects, including:
Liver problems
Crizotinib can cause liver damage or be life-threatening. Your doctor should do blood tests at least every month to check your liver while you are taking Crizotinib. Tell your doctor right away if you experience any of the following:
Your white skin or eyes turn yellow
feeling tired
dark or brown (tea-colored) urine
nausea or vomiting
have appetite
pain on the right side of your stomach
bleeding or bruising is easier than usual
itching
Lung problems (pneumonia)
Crizotinib may cause life-threatening swelling or swelling or pneumonia during treatment. Symptoms may be similar to those from lung cancer. Tell your doctor right away if you have any new or worse symptoms, including:
difficulty breathing or breathing problems
cough with or without mucus
fever
Heart problems
Crizotinib can cause very slow, very fast, or irregular heartbeats. Your doctor may check your heart during treatment with Crizotinib. Tell your doctor right away if you feel dizzy, or weak, or have an irregular heartbeat. Tell your doctor if you take any heart attack or blood pressure medication.
Vision problems
CRIZOTINIB can cause partial or total vision loss in one or both eyes. Tell your doctor right away if you have vision loss or tell your doctor if you have any visual changes such as difficulty seeing from one or both eyes. Your doctor may stop treatment with CRIZOTINIB and refer your eye doctor if you experience severe vision problems while taking CRIZOTINIB.
Pregnant
If you are pregnant, or plan to become pregnant, Crizotinib could harm your unborn baby. Women who could become pregnant should use effective methods of contraception during treatment with Crizotinib and for at least 45 days after the last dose of Crizotinib. Men who take Crizotinib, who have a possible female partner who can become pregnant, should use birth control during treatment and for at least 90 days after stopping Crizotinib. Talk to your doctor about birth control methods that may be right for you. If you or your partner becomes pregnant, tell your doctor right away.
Crizotinib 250mg Crizotinib Treatment for Chip Cancer (1)
How much does Crizotinib 250mg?
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Where to buy Crizotinib Crizix 250mg?
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Note: Information on the drug Crizonix above related to the effects of the drug and its use for the purpose of sharing knowledge, introducing information about the drug for medical staff and patients to refer. Depending on the situation and the location, there will be a separate prescription and treatment. Patients are not allowed to arbitrarily use drugs, all information on drug use must be prescribed by professional doctors.
Disclaimer: Thuoclp English Health's goal is to provide readers with relevant and up to date information. However, because drugs interact differently from person to person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always talk with your doctor or health care provider about possible interactions with all prescription medications, vitamins, herbs, and over-the-counter supplements and medications you are taking.
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