Giotrif 40mg Afatinib for lung cancer? Giotrif drug prices

Basic information about the drug Giotrif for treating lung cancer
Brand Name: Giotrif
Active ingredient: Afatinib
Content: 40mg
Form: Tablets
Packing: 1 box of 28 tablets
Manufacturer: Boehringer Ingelheim
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Giotrif supplement 40mg of Afatinib for cheese cancer (3)
What is Giotrif medicine?
Giotrif 40mg is a medicine used to treat a type of lung cancer called non-small cell lung cancer. It is used especially in adults with advanced cancer in the following situations:
when the cancer has a gene mutation for a protein called EGFR and has not previously been treated with a tyrosine kinase inhibitor.
when the cancer belongs to the squamous cell type (from the cells of the pleura) and has worsened despite chemotherapy based on platinum.
The drug contains active ingredient Afatinib , active ingredient Afatinib belongs to the group of tyrosine kinase inhibitors used to treat non-small cell lung cancer (NSCLC); There is some new evidence that the drug works against some other types of cancer, such as breast cancer.
Indications for drug treatment
Giotrif monotherapy is indicated for the treatment of locally advanced non-small cell lung cancer; or epidermal growth factor receptor (EGFR) metastasis in an adult patient who has not previously been treated with the EGFR inhibitor Tyrosine Kinase.
Contraindications to the use of drugs
Severe liver failure or kidney failure, dialysis.
Pregnant women, ensure contraception in women and continue for 1 month after treatment and lactation.
Information about dosage and administration of Giotrif
Dosage drug Giotrif
Use exactly as directed by your doctor. Follow the directions on your prescription label carefully.
The recommended dose for the treatment of advanced non-small cell (metastatic) lung cancer (NSCLC) is 40 mg orally once daily.
The recommended dose for the treatment of advanced (metastatic) psoriasis NSCLC even though platinum-based chemotherapy is 40 mg once daily.
Your healthcare provider may reduce the dose for severe kidney failure, diarrhea, or skin reaction.
How to use medicine?
Take the medicine exactly as your doctor tells you to take it.
Your doctor will tell you how much Giotrif to take and when to take it. Do not change your dose or stop taking it unless your doctor tells you to.
Drink on an empty stomach at least 1 hour before meals or 2 hours after meals.
If you miss a dose, take it as soon as you remember. If within 12 hours of your next dose, skip the dose and take the next dose only at the regular time.
Do not take 2 doses at the same time.
Giotrif supplement 40mg of Afatinib for cheese cancer (2)
Advice from a specialist at Hanoi University of Medicine and Pharmacy
Before taking Giotrif, you should pay attention to the following:
Tell your doctor and pharmacist if you are allergic to the drug or any of its ingredients. Check with your pharmacist for a list of ingredients.
Tell your doctor and pharmacist if you are taking any prescription or over-the-counter medicines, herbs, or supplements, especially:
Amiodarone (Cordarone, Pacerone);
Some antifungals such as itraconazole (Sporanox) and ketoconazole (Nizoral);
Cyclosporine (Gengraf, Neoral, Sandimune);
Erythromycin (EES, Erythrocin, ...);
HIV medications such as nelfinavir (Viracept), ritonavir (Norvir, Kaletra), and saquinavir (Invirase);
Some anticonvulsants such as carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, phenytoin (Dilantin);
Quinidine (in Nuedexta);
Rifampin (Rimactane, Rifadin, in Rifater);
Tacrolimus (Prograf);
Verapamil (Calan, Covera, Isoptin, Verelan).
There are many drugs that can interact with Giotrif that are not on the list, so make a list of all the drugs you are using with your doctor, even those not on the list above. Your doctor may change your dose of medication or monitor carefully for signs of side effects.
If you are pregnant or plan to become pregnant, or are breast-feeding. Do not breast-feed during treatment. Do not start pregnancy while on medication, wait at least two weeks after treatment. Consult your doctor about suitable contraception. If you become pregnant while taking this medication, tell your doctor. The drug can harm an unborn baby.
Things to keep in mind if you are pregnant or breast-feeding
There are not enough studies to determine the risks of taking this drug during pregnancy or lactation. Always consult your doctor before taking a drug to weigh the benefits and risks.
According to the US Food and Drug Administration (FDA), this drug belongs to class D for pregnancy. D = There is evidence of risk;
What to do in case of overdose?
Call 911 or go to the nearest local Medical Station right away.
Of course, you need to keep a record and bring a list of all medications you have taken, including prescription and over-the-counter.
What to do if I miss a dose?
If you forget to take a dose, take it as soon as possible.
But if it is almost like the next dose, skip the missed dose and take your next dose at the time as planned.
Do not take double the prescribed dose.
Side Effects of Giotrif 40mg
Important things to remember about medication side effects:
Most people will not feel all of the side effects
Drug side effects are often predictable in terms of their onset, duration, and severity.
Medication is almost always reversible and will go away after treatment is complete.
Giotrif's side effects can be quite easily managed. There are many options for minimizing or preventing side effects from medications.
The following side effects are common (occurring by more than 30%) in patients:
Diarrhea
Acne eruptions (group of acne-like skin conditions)
Mouth sores
Paronychia (nail infection)
Dry mouth
These are the less common side effects (occurring in 10-29%) for patients taking Giotrif:
Reduce appetite
Itching
Weight loss
Nosebleed
Cystitis (bladder infection)
Inflammation of the lips (cheilitis)
Fever
Hypokalemia (low potassium)
Conjunctivitis (pink eye)
Rhinitis (runny nose)
High liver enzymes
Not all of the side effects are listed above. Some rare cases (occurring in less than 10% of patients) are not listed here. Always notify your doctor if you experience any unusual symptoms.
Drug storage
Store below 30 degrees C
Avoid light and moisture
Keep the Product out of reach of children and pets
Shelf life is 36 months.
Giotrif supplement 40mg of Afatinib for cheese cancer (4)
Note: The information in the above article on Giotrif related to its effects and its use for the purpose of sharing knowledge and introducing information about the drug for medical staff and patients to refer. Depending on the situation and the location, there will be a separate prescription and treatment. Patients are not allowed to arbitrarily use drugs, all information on drug use must be prescribed by professional doctors.
Author Dr. Tran Ngoc Anh