Sandimmun Neoral 25mg drug for the prevention of graft rejection, rheumatoid arthritis is made in Germany. Medications that lower your body's immune system. The immune system helps your body fight off infections. The immune system can also fight or "reject" a transplanted organ such as the liver or kidney. This is because the immune system views the new organ as an invader.
The drug Neoral 25mg Ciclosporin prevents organ transplant rejection, anti-inflammatory.
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Indications for the use of the drug Neoral 25mg
Neoral is used to prevent organ rejection after a kidney, heart or liver transplant.
The drug Neoral 25mg is also used to treat severe psoriasis or severe rheumatoid arthritis.
Contraindications to the use of the drug Neoral 25mg
People allergic to Cyclosporin or hypersensitivity to any substance of the drug Neoral 25mg.
People with abnormal kidney function.
People with uncontrolled high blood pressure.
Pregnant women need to be prescribed by a doctor.
Breastfeeding women. Ciclosporin is distributed in milk, because it can have serious adverse effects on breastfed infants, avoiding breastfeeding when the mother is taking ciclosporin.
Dosage of the drug Neoral 25mg
Solid organ transplant: 10-15 mg / kg in 2 divided doses, oral, 12 hours before surgery, maintain daily x 1-2 weeks after surgery, then gradually decrease to 2-6 mg / kg / day, in 2 divided doses. .
Bone marrow transplant: intravenous infusion: use 1 day before transplanting 3-5 mg / kg / day, maintained for 2 weeks; oral dose: 12.5-15 mg / kg / day, 1 day before transplant, then take 12.5 mg / kg in 2 divided doses x 3-6 months; Gradually reduce the dose to 0 within 1 year.
Endogenous uveitis: oral dose of 5 mg / kg / day in 2 divided doses, possibly increased to 7 mg / kg / day & prednisone 0.2-0.6 mg / kg / day. Maintenance: reduce the dose gradually, not exceeding 5 mg / kg / day during the retreat period.
Psoriasis: 5 mg / kg / day orally in 2 divided doses, the dose may be increased gradually after 1 month, up to 5 mg / kg / day.
Atopic dermatitis: 5-5 mg / kg / day in 2 divided doses, the average course of 8 weeks. Rheumatoid arthritis: 3 mg / kg / day in 2 divided doses for the first 6 weeks, maximum 5 mg / kg x 12 weeks. Maintain: titrate according to the individual patient.
Nephrotic syndrome: adults: 5 mg / kg / day, children: 6 mg / kg / day in 2 divided doses. Maintenance: reduce the dose gradually.
How to use the drug Neoral 25mg
Should be taken with food: The daily dose should always be divided into 2 doses, swallowing the whole capsule. Avoid sharing grapefruit juice.
Use Neoral 25mg regularly to get the most out of it. To help you remember, take it at the same time every day.
It may take up to 4 months before you get the full benefits of Neoral 25mg in the treatment of rheumatoid arthritis and psoriasis.
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Advice from experts at Hanoi University of Pharmacy
Tell your doctor if you have one of the following conditions:
Kidney disease;
Untreated or uncontrolled high blood pressure.
Any type of cancer.
If you are being treated for psoriasis, you should not receive ultraviolet (PUVA or UVB) treatment, radiation therapy, or drugs that weaken the immune system (such as methotrexate) while you are on Neoral.
Neoral reduces the blood cells that help the body fight infections or causes the body to overproduce a certain type of white blood cell. This can lead to serious illnesses, including: cancer, severe brain infection that can lead to disability or death; or the virus can cause kidney failure.
It is not yet known whether Neoral 25mg will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Cyclosporine can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking cyclosporine.
Avoid diets high in K, do not use drugs with K, diuretics to keep K.
Avoid sun exposure & UV exposure. Avoid using live attenuated vaccines.
What to do in case of overdose of Neoral 25mg?
Call 911 or go to the nearest local Medical Station right away.
Of course, you need to keep a record and bring a list of all medications you have taken, including prescription and over-the-counter.
What to do if I miss a 25mg Neoral dose?
If you forget to take a 25mg Neoral dose, take it as soon as possible.
But if it is almost like the next dose, skip the missed dose and take your next dose at the time as planned.
Do not take double the prescribed dose.
Side effects Neoral 25mg
Call your doctor at once if you have:
Change in your mental state, problems with speech or walking, vision loss (which can start to get worse and get worse quickly);
Easy bruising, unusual bleeding (nose, mouth, vagina or rectum), purple or red spots under your skin;
Pale or yellow skin, dark urine, fever, confusion, or weakness;
Dangerously high blood pressure: severe headache, blurred vision, pounding in your neck or ears, nosebleeds, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeat;
High potassium: nausea, slow or irregular heartbeat, weakness, loss of movement;
Kidney problems: little or no urinating, pain or trouble urinating, swelling in your feet or ankles, feeling tired or short of breath;
Liver problems: nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, yellowing of the skin or eyes;
Signs of infection: fever, chills, flu-like symptoms, mouth sores, skin sores, feeling light-headed or short of breath, fast heartbeat.
Common side effects may include:
Acne, increased growth of facial or body hair;
Hypertension;
Nausea, diarrhea;
Swollen or painful gums.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Warning when using the drug Neoral 25mg
Do not use together with grapefruit and grapefruit juice; because it can interact with Neoral and lead to undesirable side effects.
Avoid being around people who are sick or have infections. Tell your doctor right away if you develop signs of infection.
Do not receive a "live" vaccine while using Neoral. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, chickenpox (chickenpox), zoster (shingles), and flu (flu) vaccine. .
Avoid exposure to sunlight. Neoral 25mg can make you more susceptible to sunburn. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
For pregnant & lactating women
Pregnant women
Cyclosporin crosses the placenta.
There is still no adequate evidence of safety when administering cyclosporine to pregnant women.
Use cyclosporine during pregnancy only unless the expected benefit outweighs the potential risk to the fetus.
Breastfeeding women
Cyclosporin can be distributed in breast milk.
Since there may be serious adverse effects on breastfed infants, avoid breastfeeding while mothers are taking cyclosporine.
Interaction with the drug Neoral 25mg
Neoral can harm your kidneys. This effect increases when you also use a number of other drugs, including:
antivirals,
cholesterol-lowering medicine,
Valence,
antibiotic injection,
medicine for intestinal disorders,
drugs for the treatment of autoimmune disorders,
medicine to prevent organ transplant rejection,
reduce stomach acid (Tagamet, Zantac),
and some pain relievers or arthritis medications (including aspirin, Tylenol, Advil, and Aleve)
Neoral drug 25mg ciclosporin fetus in pregnancy (4)
How to store the drug Neoral 25mg
You should store Neoral 25mg at room temperature, dry, avoid direct sunlight exposure.
You should not store the medicine in the refrigerator.
Keep Neoral 25mg out of reach of children.
You do not throw medications in the toilet or plumbing pipes.
Note: The information in the above article about Neoral related to the effects of the drug and its use for the purpose of sharing knowledge, introducing information about the drug for medical staff and patients to refer. Depending on the situation and the location, there will be a separate prescription and treatment. Patients are not allowed to arbitrarily use drugs, all information on drug use must be prescribed by professional doctors.
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