Topamax 25mg Topiramate for treatment of epilepsy prevention | ThuocLP Vietnamese Health

 

What is Topamax 25mg?

Topamax 25mg contains the main active ingredient topiramate at 25mg content. Medicines belong to a group of drugs called antiepileptic drugs.

Drugs used to treat local epilepsy with or without general secondary seizures. It is also used for migraine prophylaxis in adults after carefully evaluated the effectiveness of other therapeutic measures.

Basic information about Topamax 25mg Topiramate

• Brand name: Topamax.
• Active ingredient: topiramate .
• Drug group: Antiepileptic drugs.
• Manufacturer: Janssen.
• Content: 15mg, 25mg, 50mg, 100mg.
• Form: Tablets.
• Packing: 1 box of 60 tablets.
• Topamax Drug Prices: COMMENTS below for pricing.

Topamax 25mg Topiramate for Epilepsy Prevention (2)

Indications for use of the drug

• Treat some types of epilepsy alone (do not use other drugs). The seizures treated were partial-onset and primary general tonic-clonic seizures.
• Treat some types of epilepsy in combination with other medications. The seizures treated were partial-onset seizures, primary general tonic-clonic seizures, and convulsions associated with lennox-gastaut syndrome.
• Migraine prevention.

Contraindications to the use of drugs

• Topamax can be taken by adults and children 2 years of age and older.
• Hypersensitivity to Topiramate or any ingredient of the drug.
• Not for pregnant women and women of reproductive age who do not use appropriate contraceptive methods.

Topamax dosage 25mg

Usually start Topamax pills at a low dose of 25mg to 50mg per day.

This will be increased over the next few weeks to the usual doses for:

• Seizures: 100mg to 200mg daily, 2 times;
• Seizures (if you take an epilepsy drug other than Topamax): 200mg to 400mg per day, 2 doses;
• Migraine: 50mg to 100mg, 2 times.

In children, the dose will depend on your child's weight. The doctor will be able to give the correct dose for your child.

How to take Topamax 25mg

• Usually it should be taken twice a day. You can take Topamax pills at any time of the day, but try to take your dose at the same time every day.
• Try to space your dose evenly throughout the day. For example, the first thing in the morning and in the evening.
• Topamax 25 tablets can be taken with or without food. Swallow your tablet whole with a glass of water. Don't chew them.
• Topamax 25mg capsules can be swallowed whole or they can be opened and sprinkled on a teaspoon of soft food, like porridge or yogurt.

What to do if I miss a dose of Topamax 25mg?

• If you miss a dose, take it as soon as you remember.
• If it is less than 8 hours before your next dose, it is better to skip the missed dose and take your next dose as usual.
• Do not take 2 doses at the same time to make up for the missed dose.
• If you miss regular doses, it can help set an alarm to remind you.
• You can also ask your pharmacist for advice on other ways to help you remember to take your medicine.

What to do if overdose?

Ask your doctor for advice right away. Taking too much Topamax 25mg can lead to serious side effects. Call your doctor right away if you overdose on the drug, the reactions such as:

• Feeling dizzy or drowsy;
• Having trouble talking;
• Blurred vision;
• Stomachache;
• Feeling confused or changing your behavior.

Note when using drugs

You should not take Topamax for long if you have high blood acid problems and are also taking metformin for diabetes. To be safe tell your doctor you have:

• Glaucoma or other eye problems;
• Diabetes, or metabolic acidosis;
• Kidney disease, kidney stones or dialysis;
• Lung disease, breathing problems;
• Eating disorder;
• Liver failure ;
• Soft or brittle bones (osteoporosis, osteoporosis);
• Growth disorders.

Topiramate in Topamax can increase your blood acidity (metabolic acidosis). This can weaken your bones, cause kidney stones, or cause growth problems in children, or harm your unborn baby. You may need blood tests to make sure you don't have metabolic acidosis, especially if you're pregnant.

The use of Topamax during pregnancy will increase the risk of birth defects, such as cleft palate, cleft palate. The use of drugs also causes seizures during pregnancy that are harmful to both mother and baby. While taking the drug you should use safe methods of contraception.

The drug may not be safe for breast-feeding while you are using this medicine. Ask your doctor about any risks.

Topamax 25mg Topiramate for Epilepsy Prevention (3)

Warning when taking Topamax 25mg?

• Do not drink alcohol. Dangerous side effects or increased convulsions may occur.
• Avoid becoming overheated or dehydrated during hot weather. Topamax pills can reduce sweating and increase body temperature, leading to life-threatening dehydration (especially in children).
• Diets ketogen or "ketosis" high in fat and low in carbohydrates can increase the risk of kidney stones. Avoid using such a diet while you are on medication.
• Topamax may cause blurred vision or cause your thinking or reactions. Avoid driving a car or operating machinery until you know how this medicine will affect you.
• Also, avoid activities that could be dangerous if you have a sudden seizure, such as swimming or climbing in high places.

What is the effect of the drug on pregnant and lactating women?

For pregnant women

• There is no solid evidence that Topamax is harmful to an unborn baby.
• But to be safe, your doctor will only advise you to take it during pregnancy if the benefits outweigh the risks.
• It is important for you and your baby to stay healthy while pregnant.
• If you become pregnant while taking Topamax, tell your doctor or nurse right away.
• Do not stop taking it without first talking to your doctor.
• If you have epilepsy, it is very important that it be treated during pregnancy because the seizure can harm you and your baby.
• If you are pregnant or trying to become pregnant and taking Topamax 25mg, you should take a higher dose of folic acid, a vitamin that helps your baby develop normally.
• Your doctor may prescribe a high dose of 5mg per day for you while you are trying to get pregnant and during the first 12 weeks of pregnancy.

For breastfeeding

• Nếu bác sĩ của bạn nói rằng em bé của bạn khỏe mạnh, Topamax thuốc có thể được thực hiện trong khi bạn đang cho con bú.
• Thuốc Topamax truyền vào sữa mẹ, nhưng không có khả năng gây ra bất kỳ tác dụng phụ nào cho em bé của bạn.
• Nó có liên quan đến tác dụng phụ ở rất ít trẻ bú sữa mẹ.
• Nếu bạn nhận thấy rằng em bé của bạn không bú bình thường, hoặc có vẻ buồn ngủ bất thường, hoặc bạn có bất kỳ mối quan tâm nào khác về chúng, hãy nói chuyện với dược sĩ, khách thăm sức khỏe hoặc bác sĩ càng sớm càng tốt.

Tình trạng sức khỏe

Tình trạng sức khỏe có thể ảnh hưởng đến việc sử dụng sản phẩm. Một số tương tác có thể làm tình trạng sức khỏe trở nên tồi tệ hơn hoặc làm giảm tác dụng của thuốc. Bạn hãy báo với bác sĩ tình trạng sức khỏe hiện tại trước khi sử dụng thuốc.

Các tình trạng sức khỏe có thể làm ảnh hưởng đến tác dụng của thuốc Topamax bao gồm:

• Glaucoma or other eye problems;
• Diabetes or a history of metabolic acidosis;
• Have kidney problems, or have a history of kidney stones, or are on dialysis;
• Have serious breathing problems;
• Have a history of mental illness, depression, or have had suicidal thoughts or behaviors;
• Liver disease;
• Growth disturbances;
• Soft or brittle bones (osteoporosis, osteoporosis);
• Diarrhea.

Side effects when using Topamax 25mg

Like all medicines, Topamax can cause side effects, although not everyone gets them.

Common side effects when taking Topamax

These common side effects can occur in more than 1 in 100 people. They are usually light and walk on their own.

Keep taking the medicine, but talk to your pharmacist or doctor if these side effects bother you or do not go away:

• Feeling nauseous;
• Feeling sleepy, dizzy, or tired;
• Diarrhea;
• Feeling pressured;
• Loss of appetite or weight loss.

Serious side effects:

• Blurred vision, difficulty seeing, and eye pain.
• Pain in the back, abdomen or side, burning sensation when urinating, cloudy or smelly
• Feeling sleepy, loss of appetite, irregular heartbeat, and fainting.
• Think your child is not sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Interactions may occur with the drug Topamax

Interaction with other drugs

There are several drugs that can interfere with the effects of Topamax.

Tell your doctor if you are taking any of these medications:

• Drugs used to treat diabetes, such as: metformin, glibenclamide and pioglitazone.
• Drugs used to treat depression or anxiety, such as: venlafaxine and amitriptyline.
• Medicines to treat heart or blood pressure problems, such as: diltiazem, hydrochlorothiazide, and propranolol.
• Antipsychotic drugs, such as: risperidone.
• Any other epilepsy medicine.

Interaction with food, drink

Topamax 25mg can interact with certain foods and alcoholic beverages, alter the action of the drug or increase the risk of serious side effects. Therefore, you should consult with your doctor about the issue of eating, drinking, and using alcohol and tobacco while taking the medicine.

Topamax 25mg Topiramate for Epilepsy Prevention (4)

Drug storage

• Store the drug in a cool, dry place, avoid direct sunlight and away from moisture.
• The suitable temperature for storing the drug is <25 ° C.
• Keep the medicine out of the reach of children and young children.
• Note that medicines no longer used in household waste should not be disposed of as this can cause environmental pollution. Therefore, it is necessary to treat it before releasing it into the environment.

Note: The information in the above article about Topamax 25mg is related to the effects of the drug and its usage for the purpose of sharing knowledge and introducing drug information for medical staff and patients to refer. Depending on the situation and the location, there will be a separate prescription and treatment. Patients are not allowed to arbitrarily use drugs, all information on drug use must be prescribed by professional doctors.

Disclaimer: ThuocLP Vietnamese Health's goal is to provide readers with relevant and up to date information. However, because drugs interact differently from person to person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always talk with your doctor or health care provider about possible interactions with all prescription medications, vitamins, herbs, and over-the-counter supplements and medications you are taking.

Author Dr. Tran Ngoc Anh

 Articles are quoted from sources: https://thuoclp.com/san-pham/thuoc-topamax-25mg-topiramate/