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Tykerb pills 250mg of lapatinib to treat cancer (4)
What is Tykerb?
The drug Tykerb (lapatinib) is a cancer drug that interferes with the growth and spread of cancer cells in the body.
The drug is used to treat a hormone-related breast cancer that has progressed or spread after treatment with other cancer drugs.
In postmenopausal women, the drug is combined with a hormonal drug called Femara (letrozole). In others, the drug is taken with a cancer drug called Xeloda (capecitabine).
Tykerb dosage 250mg
Dosage of the drug Tykerb for adults
Usual adult dose for HER2-positive breast cancer metastasis:
Initial dose: you take 1250 mg (5 tablets) orally once a day on days 1 to 21 years of age continuously in combination with capecitabine.
Usual adult dose for HER2-positive breast cancer metastasis, hormone receptor-positive:
The recommended dose is 1500 mg orally once a day continuously in combination with letrozole.
Dosage of the drug Tykerb for children
Dosage for children has not been studied and decided yet. Consult your doctor if you plan on giving this medicine to your child.
How to use medicine
Take exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
When used with Femara, the usual dose of the drug is 6 pills to be taken once a day. Femara is also performed every day.
When used with Xeloda, the drug is usually taken over a 21-day cycle. You will take 5 capsules once daily for 21 consecutive days. You will take Xeloda twice daily for just the first 14 days of your cycle. This 21-day cycle was then repeated.
Your doctor will tell you how much Xeloda or Femara to take. Follow your doctor's medication instructions very carefully.
Take on an empty stomach, at least 1 hour before or 1 hour after a meal.
You can swallow the pills one at a time, but take the entire dose (all 5 or 6 pills) at the same time every day.
Xeloda should be taken with food or within 30 minutes after eating.
You will need blood tests every 4 to 6 weeks to check your liver function. Your heart function may also need to be checked using an electrocardiogram or ECG (sometimes called an EKG).
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
Your doctor will determine how long you should treat Tykerb and Xeloda or Femara. Take the drug for the full prescribed length of time. Combination chemotherapy is usually continued unless your condition gets worse or you have serious side effects.
Advice from a specialist at Hanoi University of Medicine and Pharmacy
Do not use if you are pregnant. It can harm an unborn baby.
It can cause serious problems or death in the liver.
Call your doctor at once if you have signs of liver problem: upper stomach pain, itching, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
Before you take Tykerb, tell your doctor if you have heart disease, liver disease, electrolyte imbalance (low potassium or magnesium), or a personal or family history of long QT syndrome.
Please use on an empty stomach. Take this medicine for the entire time prescribed by your doctor.
What should be noted before using the drug?
Do not use if you are allergic to the active ingredient lapatinib found in Tykerb. For your safety, tell your doctor if you have:
Heart disease;
Liver disease (lapatinib can cause serious or fatal liver problems);
An electrolyte imbalance (such as low levels of potassium or magnesium in your blood); either a personal or family history of long QT syndrome.
Do not use if you are pregnant. It can harm an unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine. Tell your doctor right away if you become pregnant.
It is not known whether lapatinib active ingredient passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking Tykerb.
What to do in case of overdose?
Call 911 or go to the nearest local Medical Station right away.
Of course, you need to keep a record and bring a list of all medications you have taken, including prescription and over-the-counter.
What to do if I miss a dose?
If you forget to take a dose, take it as soon as possible.
But if it is almost like the next dose, skip the missed dose and take your next dose at the time as planned.
Do not take double the prescribed dose.
Tykerb pills 250mg of lapatinib to treat cancer (2)
Tykerb side effects
Get emergency medical help if you have signs of an allergic reaction: hives; shortness of breath; swelling of your face, lips, tongue, or throat.
Tykerb 250mg can cause serious or fatal liver problems. Call your doctor right away if you have: upper stomach pain, itching, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
Also call your doctor at once if you have:
Headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
Severe or persistent diarrhea;
Cough or wheezing, wheezing, chest pain, feeling short of breath; or
Severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, then a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects when taking the drug:
Indigestion, loss of appetite;
Nausea, vomiting, diarrhea;
Rash, itching, dry skin;
Pain or redness on the palms of the hands or soles of the feet;
Problems with your nails or toenails;
Feeling weak or tired;
Nosebleeds, mouth sores;
Thin hair; or
Headache.
Tykerb pills 250mg of lapatinib to treat cancer (3)
Tykerb drug interactions 250mg
Tell your doctor about all your current medicines and any you start or stop using, especially:
Antacids or stomach acid reducers such as Prilosec or Nexium;
Antibiotics or antifungals;
Antidepressants;
Heart or blood pressure medication;
Medicines to treat HIV or AIDS;
Anticonvulsants;
St. John's wort.
This list is not exhaustive. Other drugs may interact with the active ingredient lapatinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
How to store drugs
You should store the drug at room temperature, dry, avoid direct sunlight exposure.
You should not store the medicine in the refrigerator.
Keep medicine out of reach of children.
You do not throw medications in the toilet or plumbing pipes.
How much does Tykerb 250mg lapatinib cost?
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Please comment below for us to answer about Medication
Note: The information in the above article about Tykerb 250mg related to the effects of the drug and its usage for the purpose of sharing knowledge, introducing drug information for medical staff and patients to refer. Depending on the situation and the location, there will be a separate prescription and treatment. Patients are not allowed to arbitrarily use drugs, all information on drug use must be prescribed by professional doctors.
Disclaimer: ThuocLP's goal is to provide readers with relevant and up to date information. However, because drugs interact differently from person to person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always talk with your doctor or health care provider about possible interactions with all prescription medications, vitamins, herbs, and over-the-counter supplements and medications you are taking.
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