Abirapro medicine 250mg Abiraterone prostate cancer
- Brand Name: Abirapro
- Active ingredient: Abiraterone
- Manufacturer: Glenmark Pharmaceuticals Ltd
- Content: 250 mg
- Form: Tablets
- Packaging: Bottle of 120 tablets
- Drug quotation: Contact directly or leave a comment here typing "Abirapro".
What is Abirapro 250mg?
Abirapro Tablet is an anti-cancer medicine used in men along with a medicine called prednisone to treat prostate cancer that has spread to other parts of the body.
It is often used in patients who have not responded to other treatments.
Mechanism of action of the drug Abirapro 250mg to treat prostate cancer
A steroidal enzyme inhibitor CYP17A1 (17 alpha-hydroxylase/C17.20 lyase) called abirateron acetate is an orally active substance and it interferes with CYP17A1 in a selective and immutable manner through an additive binding mechanism. Valence. A CYP17A1 enzyme that catalyzes androgen biosynthesis and is highly expressed in testicular, adrenal, and prostate tumor tissue.
In particular, abiraterone blocks the conversion of 17-hydroxyprognenolone to dehydroepiandrosterone (DHEA) by the enzyme CYP17A1 to reduce serum levels of testosterone and other androgens.
What are the indications for Abirapro 250mg?
Use Abirapro 250 mg Tablet
- Metastatic prostate cancer
- Medicines used in the treatment of prostate cancer that have spread to other parts of the body.
- It is often used in patients who have not responded to other treatments.
Contraindications to the drug abirapro?
Allergies: Abirapro is not recommended for use in patients who are allergic to abiraterone or any of its ingredients.
Pregnancy: The drug is not recommended for use in pregnant women.
Drug dosage
- Abirapro is recommended to take 1,000 mg (four 250 mg tablets) once a day.
- Do not take the medicine with food in the stomach.
- The drug interacts with food in the stomach will cause dangerous side effects.
Recommended dosage for patients with hepatic impairment
- In patients with moderate hepatic impairment (Child-Pugh Class B), the recommended dose of Abirapro should be reduced to 250 mg once daily.
- If there is still no improvement in the side effects of the drug, the patient should stop using Abirapro.
- Patients with severe liver failure absolutely should not take this drug.
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