Keytruda Pembrolizumab 100mg / 4ml for targeted cancer treatment | ThuocLP Vietnamese Health

 

What is Keytruda medicine?

Keytruda treats several types of cancer, including several types: skin cancer, lung cancer, head and neck cancer, lymphoma, bladder cancer, stomach cancer, esophageal cancer, cancer cervical cancer, liver cancer, kidney cancer, endometrial cancer.

A prescription drug that has been approved by the FDA. The drug contains the active ingredient Pembrolizumab; A group of drugs known as PD-1 inhibitors.

Keytruda 100mg / 4ml Pembrolizumab is a targeted cancer treatment drug

• Brand name: Keytruda.
• Active ingredient: Pembrolizumab.
• Content: 100mg / 4ml.
• Form: Solution for injection.
• Package: 1 bottle of 100mg / 4ml of infusion solution.
• Manufacturer: MSD.
• Keytruda drug prices: COMMENTS at the end of the article.

Keytruda 100mg 4ml Pembrolizumab for Central Cancer Treatment (2)

Indications for treatment

• Keytruda drug for nonresectable or metastatic malignancies.
• Patients with non-small cell metastatic lung cancer (NSCLC) with tumors expressing PD-L1 and those with disease progressing on or after chemotherapy.
• Treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) with disease progression on or after chemotherapy.
• Indications for the treatment of advanced or metastatic urothelial carcinoma with disease progression during or after chemotherapy.

Note: If a drug has been approved for one use, doctors may decide to use this same drug for other problems if they believe it could be helpful.

Contraindicated for use

Patients with hypersensitivity to the active ingredient Pembrolizumab or to any of the excipients of the drug.

Keytruda drug dosage

• The use of drugs requires the appointment of a doctor, so that the correct dose can be adjusted to suit each patient.
• With malignant neoplasms that cannot be resected and metastasized: 200 mg dose by intravenous infusion for 30 minutes, every 3 weeks.
• Non-small cell lung cancer: IV dose of 200 mg for 30 minutes, every 3 weeks until disease progresses or for up to 24 months in non-advanced patients.

How to use the drug Keytruda

• The drug Keytruda is given as an intravenous injection through a vein (IV) over 30 minutes every 3 weeks.
• The dose of medication you will receive depends on many factors, including: your weight, your health and the type of cancer or disease being treated. Your doctor will determine your dose and schedule.

What to do in case of an overdose of Keytruda?

• Call 911 or go to the nearest local Medical Station right away.
• Of course, you need to keep a record and bring a list of all medications you have taken, including prescription and over-the-counter.

What to do if I miss a dose?

• If you forget to take a dose, take it as soon as possible.
• But if it is almost like the next dose, skip the missed dose and take your next dose at the time as planned.
• Do not take double the prescribed dose.

Keytruda cancer drug side effects

The following side effects are common:

• Anemia;
• Tired;
• Hyperglycemia;
• Hyponatremia;
• Reduce albumine;
• Itching;
• A cough;
• Nausea.

One side effect is a more rare side effect when taking Keytruda:

• Rash;
• Anorexia;
• Increased triglycerides;
• Increased liver enzymes;
• Diarrhea;
• Athritis;
• Shortness of breath;
• Headache;
• Vomiting;
• Chills;
• Myalgia;
• Insomnia;
• Stomachache;
• Backache;
• Fever;
• Vitiligo;
• Dizziness;
• Upper respiratory tract infection.

Not all of the side effects are listed above. Some of which are very rare (occurring in less than 10% of patients) are not listed here. However, you should always notify your doctor if you experience any unusual symptoms.

Keytruda 100mg 4ml Pembrolizumab for Central Cancer Treatment (3)

Warnings when taking the drug Keytruda

Keytruda pills can change the way your immune system works, which can cause a number of side effects that could lead to serious medical problems.

Before starting treatment make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbs, etc.).

Do not receive any type of vaccination or immunization not approved by your doctor while taking the drug.

Medications can cause side effects in many different parts of your body. Some side effects may need to be treated with other drugs and your cancer treatment may be delayed.

For both men and women: Do not become pregnant while either the parent is using Keytruda; use a safe method of contraception during the period of use of the drug, after treatment for at least 4 months.

For pregnant & lactating women

Stop using the medicine or stop breastfeeding if you are about to use the medicine.

There should be a method of contraception during the use of the drug, should only get pregnant after at least 4 months of stopping the drug.

Self-care tips for Keytruda 100mg treatment

• Drink at least 2-3 liters of fluids every 24 hours, unless you are instructed otherwise.
• If you should experience nausea, take anti-nausea medications as prescribed by your doctor, and eat small meals regularly. Sucking and chewing gum may also help.
• Avoid sun exposure Wear SPF 30 (or higher) sunscreen and protective clothing.
• In general, alcohol intake should be kept to a minimum or completely avoided. You should discuss this with your doctor.
• Use an electric shaver to minimize bleeding
• Rest much.
• Maintain good nutrition.
• Wash your hands often.
• You may be at risk of infection, reported fever or any other signs of infection right away to your healthcare provider. Try to avoid crowds or people with colds, and report fever or any other signs of infection right away to your healthcare provider.
• Talk with your healthcare provider before taking any other medicines including prescription and herbal.
• To avoid mouth sores use a soft toothbrush, and wash three times a day with ½ to 1 teaspoon of baking soda and / or ½ to 1 teaspoon of salt mixed with 8 ounces of water.
• If you experience symptoms or side effects, be sure to discuss them with your healthcare team. They may prescribe medications and / or suggest other offers effective in managing such problems.

Keytruda 100mg 4ml Pembrolizumab for Central Cancer Treatment (1)

Drug interactions Keytruda pembrolizumab

A drug can interact with the drug Keytruda. But these are not the only drugs that can interact with this medication.

Keytruda and acidinib

Taking it with another cancer drug called acidinib (Inlyta) increases your risk of liver damage. This risk increases compared to using Keytruda alone.

Possible liver damage symptoms include:

• Nausea or vomiting;
• Jaundice (yellowing of the skin or the whites of the eyes);
• Pain in the right side of the abdomen;
• Dark or cloudy urine;
• Bruising more often than usual;
• Bleeding doesn't stop.

If you are taking Keytruda in combination with acidinib, your doctor will closely monitor your liver function. They will do this by testing some blood tests.

If you have any symptoms of liver damage during treatment, call your doctor right away.

Besides, before taking any medication, talk to your doctor and pharmacist. Tell them about all your prescription, over-the-counter and other medicines you take. Also tell them about any vitamins, herbs, and supplements you take. Sharing this information can help you avoid potential interactions.

How to store drugs

• You should store the medicine Store in the refrigerator (2 ° C - 8 ° C).
• Keep medicine out of reach of children.
• You do not throw medications in the toilet or plumbing pipes.

Note: The information in the above article about thedrug Keytruda 100mgis related to its effects and its use for the purpose of sharing knowledge and introducing information about the drug for medical staff and patients to refer to. Depending on the situation and the location, there will be a separate prescription and treatment. Patients are not allowed to arbitrarily use drugs, all information on drug use must be prescribed by professional doctors.

Disclaimer: ThuocLP Vietnamese Health's goalis to provide readers with relevant and up to date information. However, because drugs interact differently from person to person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always talk with your doctor or health care provider about possible interactions with all prescription medications, vitamins, herbs, and over-the-counter supplements and medications you are taking.

Author Dr. Tran Ngoc Anh

 Articles are quoted from sources:

https://nhathuoconline.org/thuoc-ung-thu/ung-thu-phoi/thuoc-keytruda/