Drug information Megace
- Brand Name: Megace 160mg
- Active ingredient: Megestrol
- Manufacturer: Deva
- Content: 160mg
- Form: Tablets
- Packaging: Box of 30 tablets
What is Megace?
Megace 160mg is a prescription medicine used to treat the symptoms of loss of appetite and wasting syndrome in patients with AIDS -Related cachexia , breast cancer or endometrial cancer . Megace can be used alone or with other medicines.
Megestrol is used to relieve symptoms and reduce suffering from advanced breast cancer and advanced endometrial cancer (cancer that begins in the lining of the uterus).
Megestrol is used to treat anorexia, malnutrition, and severe weight loss in patients with acquired immunodeficiency syndrome (AIDS). Megestrol should not be used to prevent anorexia and severe weight loss in patients who have not developed this condition.
Megestrol is a man-made version of the human hormone progesterone. The drug treats breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It increases weight by increasing appetite.
How does Megacet work?
Megestrol is a type of hormone therapy. Hormones are chemicals produced by glands in the body that enter the bloodstream and cause effects on other tissues. (For example, the hormone testosterone made in the testicles is responsible for male characteristics such as a deeper voice and increased body hair.)
The use of hormone therapy to treat cancer is based on the observation that receptors for specific hormones required for cell growth are located on the surface of some tumor cells. Hormone therapies work by; stop producing a certain hormone, block hormone receptors, or substitute chemical analogues for the active hormone that tumor cells cannot use.
Megestrol is a progestin (a man-made form of the hormone progesterone). It has properties that interfere with the normal estrogen cycle. This interferes with the stimulation of cell growth in estrogen-dependent tumor cells. It is also thought to have some direct effect on the lining of the uterine wall (endometrium).
One side effect of megestrol is weight gain. The exact mechanism of this effect is still unclear, but the effect leads to increased body fat. Taking advantage of this side effect, megestrol has been studied and used to treat severe anorexia (anorexia), muscle weakness (weakness), and weight loss associated with cancer and AIDS.
How much is the dose of Megace?
Megace is recommended to be used according to the doctor's prescription, do not arbitrarily determine the therapeutic dose without a diagnosis.
The recommended dose of the drug is 160mg/day, requiring a minimum of 2 months of treatment to determine the therapeutic effect of the drug. Because the time of effect showing hormonal changes is usually quite long.
Missed dose of Megace
The missed dose should be taken as soon as possible. You should skip the missed dose if it is time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.
Overdosage of Megace
- Seek immediate medical attention or contact your doctor if an overdose of Megace is suspected.
- Bring your Megace prescription and box to your doctor.
How to take Megace
Take Megace exactly as prescribed by your doctor. Follow all directions on your medication label and read all medication instructions or instruction sheets. Your doctor may sometimes change your dose. Use the medication exactly as directed.
Megace side effects
These are the less common side effects (occurring in 10-29%) for patients taking megestrol:
- Weight gain
- Edema (swelling, usually in the feet or hands)
- Sudden menstrual bleeding, bleeding
Not all side effects are listed above, some rare side effects (occurring in less than 10% of patients) are not listed here. However, you should always notify your healthcare provider if you experience any unusual symptoms.
Precautions while using Megace
Before taking this medicine, you should tell your doctor or pharmacist if:
- You are pregnant or breastfeeding. You need to take the medicine prescribed by your doctor in this case;
- you are allergic to any of the ingredients in megestrol;
- you are taking other medicines (including prescription and over-the-counter medicines, herbs and supplements);
- You plan to give the medicine to children or the elderly;
You have or have ever had the following medical conditions:
- Kidney disease;
- Liver failure;
- Diabetes;
- Adrenal gland disorders;
- History of stroke or blood clot.
Things to keep in mind when taking megestrol in special cases (pregnancy, lactation, surgery, etc.)
There are not enough studies to determine the risks of taking this medicine during pregnancy or breast-feeding. Before taking medication, always consult with your doctor to weigh the benefits and risks.
Megacet drug interactions
Tell your doctor about all your other medicines, especially of: Blood thinners-warfarin, Coumadin, Jantoven.
This list is not exhaustive. Other drugs can affect megestrol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
See interaction reports for Megace (megestrol) and the drugs listed below.
- Amlodipine, Aricept (donepezil), aspirin , folic acid
- Clonidine, Cymbalta (duloxetine)
- Dexamethasone, docusate
- Lasix (furosemide), Lisinopril, Lyrica (pregabalin)
- MiraLAX (polyethylene glycol 3350)
- multivitamins
- omeprazole, ondansetron
- potassium chloride
- prednisone
- Tylenol (acetaminophen)
- Xanax (alprazolam)
Zofran (ondansetron)
Megace disease (megestrol) interactions
There are 5 disease interactions with Megace (megestrol) including:
- Thromboembolism
- Stay hydrated
- Retinal Thrombosis
- Diabetes
- Adrenal cortex
How should Megace be stored?
- Store at controlled room temperature 15° – 30°C
- Protect this medication from light and moisture.
- Do not use the medicine beyond the expiry date indicated on the outside of the medicine box.
- Do not dispose of medication in sewage or household waste. Ask your pharmacist how to discard these unused medicines. This will help protect the environment. See more information on drug storage.
Drug Megace cost how much?
- Megace drug prices will have certain fluctuations between pharmacies, distribution agents. Users can consult prices directly at reputable drugstores nationwide.
** Note: Information about the article about Megace drug for the purpose of sharing knowledge for reference only, patients are not allowed to use the drug on their own, all information on drug use must be according to the instructions. specialist doctor.
Reference source ThuocLP Vietnamese:
https://thuoclp.com/san-pham/thuoc-megace-160mg-megestrol-acetat-30-vien/
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