Information on Ketosteril 600mg Methionine for chronic kidney failure
| Brand name | Ketosteril |
| Active | Methionine |
| Content | 600mg |
| Manufacturer | Fresenius Kabi |
| Modulation form | Tablets |
| Pack | box of 100 tablets |
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What is Ketosteril?
Ketosteril medicine contains the active ingredient Methionine 600 mg; The drug is used in cases of malnutrition, prevention and treatment of protein metabolism disorders in the body with chronic kidney failure and cases of protein deficiency due to eating.
Prophylactic and conservative treatment for patients with chronic renal failure with a glomerular filtration rate (GFC) in the range of 5-15 mL/min, in combination with a protein-restricted diet (40 g daily in adults). or less).
The drug is used for amino acid deficiency, incontinence, asthma, Paracetamol toxicity, Allergies, radiation side effects, and other conditions.
Alpha ketoanalogue The salt ingredient in the medicine belongs to a group of drugs called nutritional supplements.
The active ingredient methionine allows the intake of essential amino acids while minimizing amino-nitrogen intake. After absorption, the keto and hydroxy analogs are converted to their respective essential amino acids by taking nitrogen from the non-essential amino acids, thereby reducing urea formation by reusing the amino group. . As a result, the accumulation of uraemia toxins is reduced.
Keto and hydroxy acids do not induce ultrafiltration of the remaining nephrons. Ketoacid-containing supplements exert a positive effect on renal hyperphosphataemia and secondary hyperparathyroidism. Furthermore, renal osteodystrophy can be improved.
The use of Ketosteril in combination with a very low protein diet allows to reduce nitrogen intake while preventing the serious consequences of protein supplementation and inadequate malnutrition.
Indications for treatment of Ketosteril kidney protein tablets
- Prevention and treatment of diseases caused by disorders, impaired protein metabolism in chronic kidney disease with protein in food restricted to ≤ 40g/day (adults).
- Helps reduce symptoms caused by increased blood urea, reduce Proteinuria, prevent protein breakdown of the body
- Correcting disorders of calcium-phosphate metabolism, hyperparathyroidism and renal osteoporosis, improving disorders of carbohydrate metabolism, lipid metabolism, improving endocrine disorders.
- Usually indicated for patients with glomerular filtration rate <25mL/min.
Contraindications to use
- Patients with hypersensitivity to Methionine or any of the ingredients.
- Patients with hypercalcemia, amino acid metabolism disorders.
Dosage of Ketosteril 600mg
Adults 4-8 tablets x 3 times/day, maintenance dose: 1 tablet/ 5kg body weight/day divided into 3 times.
Dosage for adults
- Basic dose: you take 1 tablet / 5kg or 100mg / kg, divided into 3 times / day. For example, for an adult weighing 70kg, the indicated amount is 4-8 tablets divided into 3 times/day.
- You should take the full dose while your glomerular filtration rate is at 25ml/min.
- While using the drug you should consider the amount of protein put into the body. Before dialysis, protein intake should not exceed 40g/day. During dialysis, you should consult with the amount of protein that can be loaded into the body.
Dosage for children
- Consult your doctor and be careful when giving Ketosteril to your child. For children from 3-10 years old: 1.4-0.8g/kg; For children from 10 years old and above: 1-0.6g/kg.
- While using the drug you should consider the amount of protein put into the child's body. Before dialysis, protein intake should not exceed 40g/day. During dialysis, you should consult with the amount of protein that can be loaded into the body.
The amount of protein children should tolerate each day is:
- For children from 3-10 years old: 1.4-0.8g/kg;
- For children from 10 years old and above: 1-0.6g/kg.
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